ATP8A1

Across TCGA cell cohorts, ATP8A1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP8A1-associated genes across cancer lineages are IFNA14, GPR119, and LCE1A. Each is linked with ATP8A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP8A1-to-partner and partner-to-ATP8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by ATP8A1-low versus ATP8A1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8A1→partner) and Y-score (partner→ATP8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	1
OESOPHAGUS	GPR119 →	+0.040	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUSC	LCE1A →	+0.126	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	CFAP97D2 →	+0.020	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
BLOOD_Leukemia	ITIH6 →	+0.021	+4.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

IFNA14 by ATP8A1 expression — SOFT_TISSUE

Explore this box plot interactively →