ATP7A

Across TCGA patient cohorts, ATP7A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,273 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ATP7A-associated proteins across cancer lineages are RPL6, ATP7A_T327, and CASK. Each is linked with ATP7A in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP7A-to-partner and partner-to-ATP7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP7A versus RPL6 in BRCA, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP7A→partner) and Y-score (partner→ATP7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL6 →	-0.391	-0.470	<.001	.001	3	5
BRCA	ATP7A_T327 →	+0.523	+0.524	<.001	<.001	3	4
BRCA	CASK →	+0.309	+0.747	<.001	<.001	3	4
GBM	DIAPH2 →	+0.346	+0.390	<.001	<.001	3	4
LUAD	DLG3 →	+0.323	+0.362	<.001	<.001	3	4
LSCC	EPS15_S221 →	-0.340	-0.540	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,273 associations by consensus.

ATP7A vs RPL6 — BRCA

Explore this scatter interactively →