ATP7A

Across TCGA patient cohorts, ATP7A protein abundance is significantly associated with the RNA expression of many other genes, with 12,790 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP7A-associated genes across cancer lineages are ZDHHC9, BLVRB, and XIAP. Each is linked with ATP7A in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP7A-to-partner and partner-to-ATP7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP7A versus ZDHHC9 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP7A→partner) and Y-score (partner→ATP7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZDHHC9 →	+0.697	+0.257	<.001	.002	3	5
LSCC	BLVRB →	+0.659	+0.281	.001	<.001	3	5
BRCA	XIAP →	+0.508	+0.315	.001	.005	3	4
UCEC	SLC43A3 →	-0.790	-0.263	.004	.003	3	4
LSCC	GLA →	+0.663	+0.404	<.001	<.001	3	4
BRCA	MAGT1 →	+0.634	+0.406	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,790 associations by consensus.

ATP7A vs ZDHHC9 — UCEC

Explore this scatter interactively →