ATP6V1H

Across TCGA pan-cancer cohorts, ATP6V1H mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ATP6V1H data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ATP6V1H mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP6V1H expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where ATP6V1H mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	0.910	1.000	.026	30	view →
CCRCC	DFS	Tertile	All	1.000	0.850	.010	23	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
HNSC	OS	Median	All	0.939	0.991	.018	8	view →
LSCC	OS	Tertile	III,IV	0.916	0.551	.015	5	view →
GBM	DFS	Quartile	All	0.819	0.621	.049	1	view →
LUAD	OS	Quartile	All	0.704	0.832	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ATP6V1H–COAD (DFS)

Open the COAD breakdown →