ATP6V1G3

Across TCGA patient cohorts, ATP6V1G3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,902 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ATP6V1G3-associated GO terms across cancer lineages are Intrinsic apoptotic signaling pathway in response to DNA damage, Collagen metabolic process, and Cytoplasmic translation. Each is linked with ATP6V1G3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ATP6V1G3-to-partner and partner-to-ATP6V1G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intrinsic apoptotic signaling pathway in response to DNA damage grouped by ATP6V1G3-low versus ATP6V1G3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G3→partner) and Y-score (partner→ATP6V1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intrinsic apoptotic signaling pathway in response to DNA damage →	+0.076	+0.081	<.001	<.001	3	11
STAD	Collagen metabolic process →	+0.064	+0.134	<.001	<.001	3	10
STAD	Cytoplasmic translation →	+0.103	+0.114	<.001	.001	3	10
STAD	Regulation of intrinsic apoptotic signaling pathway →	+0.074	+0.070	<.001	.002	3	9
TGCT	Roof of mouth development →	+0.071	+0.331	<.001	<.001	3	9
STAD	Myeloid cell homeostasis →	+0.085	+0.165	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,902 associations by consensus.

Intrinsic apoptotic signaling pathway in response to DNA damage by ATP6V1G3 expression — STAD

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