ATP6V1G3

Across TCGA patient cohorts, ATP6V1G3 protein abundance is significantly associated with the RNA expression of many other genes, with 218 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ATP6V1G3-associated genes across cancer lineages are PQBP1, LYRM1, and USP31. Each is linked with ATP6V1G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G3-to-partner and partner-to-ATP6V1G3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1G3 versus PQBP1 in CCRCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G3→partner) and Y-score (partner→ATP6V1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PQBP1 →	-0.223	-0.412	.002	<.001	3	1
CCRCC	LYRM1 →	-0.317	-0.278	.008	.008	3	1
CCRCC	USP31 →	-0.276	-0.404	.006	.005	3	1
CCRCC	LAPTM4B →	-0.402	-0.303	.009	.004	3	1
CCRCC	LILRB5 →	+0.925	+0.542	<.001	<.001	3	1
CCRCC	SP4 →	+0.315	+0.331	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 218 associations by consensus.

ATP6V1G3 vs PQBP1 — CCRCC

Explore this scatter interactively →