ATP6V1G3

Across TCGA patient cohorts, ATP6V1G3 mutation is significantly associated with the RNA expression of many other genes, with 199 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATP6V1G3-associated genes across cancer lineages are OR10A5, CDY2A, and RNU6-1080P. Each is linked with ATP6V1G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G3-to-partner and partner-to-ATP6V1G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by ATP6V1G3-low versus ATP6V1G3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G3→partner) and Y-score (partner→ATP6V1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR10A5 →	+0.165	+4.540	<.001	.009	3	2
BRCA	CDY2A →	+0.014	+5.215	<.001	.003	3	2
BRCA	RNU6-1080P →	+0.287	+6.459	<.001	<.001	3	2
BRCA	MIR181A2 →	+1.644	+4.278	<.001	.008	3	2
BRCA	MIR329-1 →	+0.223	+6.459	<.001	<.001	3	2
BRCA	MIR921 →	+1.193	+4.841	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 199 associations by consensus.

OR10A5 by ATP6V1G3 expression — BRCA

Explore this box plot interactively →