ATP6V1G3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V1G3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ATP6V1G3-associated genes across cancer lineages are NK cells, Endothelial cells, and mv Endothelial cells. Each is linked with ATP6V1G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G3-to-partner and partner-to-ATP6V1G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by ATP6V1G3-low versus ATP6V1G3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G3→partner) and Y-score (partner→ATP6V1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNK cells →+0.004+5.597.004.04031
SKCMEndothelial cells →-0.048-2.993.030.03711
SKCMmv Endothelial cells →-0.031-2.993.039.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

NK cells by ATP6V1G3 expression — STAD

Box plot of NK cells in ATP6V1G3-low vs ATP6V1G3-high samples in STAD.

Explore this box plot interactively →

Exploration