ATP6V1G2-DDX39B

Across TCGA pan-cancer cohorts, ATP6V1G2-DDX39B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ATP6V1G2-DDX39B data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher ATP6V1G2-DDX39B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP6V1G2-DDX39B expression acts as an unfavorable survival marker, although some lineages such as LGG and GBM show a favorable association.

DLBC, CHOL, and THCA are the cancer types where ATP6V1G2-DDX39B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	II,III,IV	0.126	0.951	<.001	70	view →
CHOL	OS	Tertile	All	0.253	0.817	<.001	63	view →
THCA	DFS	Tertile	IV	0.541	0.931	.003	50	view →
LGG	OS	Median	All	0.868	0.746	<.001	39	view →
GBM	OS	Tertile	All	0.341	0.204	.003	33	view →
BRCA	OS	Quartile	All	0.885	0.535	.003	30	view →
COAD	OS	Tertile	All	0.767	0.879	.016	18	view →
OV	OS	Tertile	II,III,IV	0.236	0.346	.013	18	view →
UVM	DFS	Median	All	0.370	0.660	.019	16	view →
THYM	DFS	Tertile	III,IV	0.214	1.000	.008	9	view →
LIHC	DFS	Tertile	II,III,IV	0.127	0.431	.002	9	view →
KIRC	DFS	Tertile	II,III,IV	0.853	0.774	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ATP6V1G2-DDX39B–DLBC (DFS)

Open the DLBC breakdown →