ATP6V1FNB

Across TCGA pan-cancer cohorts, ATP6V1FNB RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ATP6V1FNB’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ATP6V1FNB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP6V1FNB is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

THCA, COAD, and KIRP are the cancer types where ATP6V1FNB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V1FNB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+1.692	<.001	11	view →
COAD	Male	II,III,IV	+1.460	<.001	11	view →
KIRP	All	II,III,IV	+1.390	<.001	11	view →
KICH	Male	All	−1.447	<.001	8	view →
LIHC	All	All	+0.387	<.001	7	view →
LUAD	Male	All	+0.522	.008	6	view →
BRCA	Female	II,III,IV	−0.187	<.001	6	view →
LUSC	Male	All	+0.582	<.001	5	view →
STAD	All	II,III,IV	+0.574	.002	5	view →
HNSC	All	All	+0.271	.004	4	view →
CHOL	All	All	+1.460	<.001	2	view →
READ	All	All	+1.153	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ATP6V1FNB–THCA

Open the THCA breakdown →