ATP6V1F

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V1F protein abundance is significantly associated with the RNA expression of many other genes, with 12,856 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP6V1F-associated genes across cancer lineages are ATP6V1B2, SIGLEC9, and FCGR1A. Each is linked with ATP6V1F in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP6V1F-to-partner and partner-to-ATP6V1F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1F versus ATP6V1B2 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1F→partner) and Y-score (partner→ATP6V1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATP6V1B2 →+0.514+0.277<.001<.00137
UCECSIGLEC9 →+0.689+0.228.003.00235
COADFCGR1A →+1.259+0.294<.001<.00135
COADFCER1G →+1.129+0.340<.001<.00135
LUADCTSB →+0.635+0.206<.001.00135
UCECCD300A →+1.036+0.266.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,856 associations by consensus.

ATP6V1F vs ATP6V1B2 — UCEC

Per-sample scatter of ATP6V1F vs ATP6V1B2 in UCEC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration