ATP6V1F

Across TCGA pan-cancer cohorts, ATP6V1F RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ATP6V1F’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP6V1F RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP6V1F is over-expressed in tumor.

COAD, HNSC, and LIHC are the cancer types where ATP6V1F tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V1F RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.467	<.001	11	view →
HNSC	All	IV	+0.625	<.001	11	view →
LIHC	Female	II,III,IV	+1.754	<.001	9	view →
BLCA	All	All	+0.579	<.001	9	view →
KIRP	All	II,III,IV	+0.600	<.001	7	view →
THCA	Female	II,III,IV	+0.482	<.001	7	view →
UCEC	All	III,IV	+0.855	<.001	6	view →
BRCA	All	III,IV	+0.790	<.001	6	view →
CHOL	Male	All	+2.481	<.001	5	view →
READ	All	All	+0.918	.002	4	view →
STAD	All	All	+0.400	.009	4	view →
ESCA	All	All	+0.962	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ATP6V1F–COAD

Open the COAD breakdown →