ATP6V1F

Across TCGA patient cohorts, ATP6V1F mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1F-associated genes across cancer lineages are RNA5SP393, RNU6-650P, and MIR1266. Each is linked with ATP6V1F in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1F-to-partner and partner-to-ATP6V1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP393 grouped by ATP6V1F-low versus ATP6V1F-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1F→partner) and Y-score (partner→ATP6V1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP393 →	+0.405	+3.766	.001	.001	3	1
UCEC	RNU6-650P →	+0.331	+3.302	.005	.009	3	1
UCEC	MIR1266 →	+0.386	+4.356	<.001	.001	3	1
UCEC	RNU6ATAC30P →	+0.605	+5.102	<.001	<.001	3	1
UCEC	MIR1251 →	+0.291	+5.148	<.001	.002	3	1
UCEC	LINC01850 →	+0.304	+3.993	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

RNA5SP393 by ATP6V1F expression — UCEC

Explore this box plot interactively →