ATP6V1F

Across TCGA cell cohorts, ATP6V1F RNA expression is significantly associated with the go_rna of many other GO terms, with 3,466 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ATP6V1F-associated GO terms across cancer lineages are Negative regulation of synaptic vesicle exocytosis, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with ATP6V1F in more than 9 cancer types. Because this analysis shows association rather than direction, both ATP6V1F-to-partner and partner-to-ATP6V1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of synaptic vesicle exocytosis grouped by ATP6V1F-low versus ATP6V1F-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1F→partner) and Y-score (partner→ATP6V1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of synaptic vesicle exocytosis →	+0.145	+1.063	<.001	<.001	3	10
BLOOD_Myeloma	Purine nucleoside triphosphate biosynthetic process →	+0.074	+0.694	<.001	.001	3	10
BLOOD_Myeloma	Purine ribonucleoside triphosphate biosynthetic process →	+0.074	+0.694	<.001	.001	3	10
SKIN	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.063	+0.752	.002	<.001	3	9
SKIN	Electron transport coupled proton transport →	+0.063	+0.752	.002	<.001	3	9
BLOOD_Myeloma	Mitochondrial electron transport, NADH to ubiquinone →	+0.094	+0.754	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,466 associations by consensus.

Negative regulation of synaptic vesicle exocytosis by ATP6V1F expression — PANCREAS

Explore this box plot interactively →