ATP6V1E2

Across TCGA patient cohorts, ATP6V1E2 protein abundance is significantly associated with the protein abundance of many other proteins, with 644 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATP6V1E2-associated proteins across cancer lineages are THBS1_S1059, THBS1_S1062, and THBS1_Y1058. Each is linked with ATP6V1E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1E2-to-partner and partner-to-ATP6V1E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1E2 versus THBS1_S1059 in BRCA, with a Pearson correlation of 0.89.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1E2→partner) and Y-score (partner→ATP6V1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	THBS1_S1059 →	+3.260	+1.058	.004	.002	3	1
BRCA	THBS1_S1062 →	+3.260	+1.058	.004	.002	3	1
BRCA	THBS1_Y1058 →	+3.260	+1.058	.004	.002	3	1
BRCA	NCKIPSD_T181 →	+0.558	+1.004	<.001	.003	3	1
BRCA	PLIN3_S196 →	+0.763	+0.960	<.001	.001	3	1
GBM	TRIM56_S475 →	-0.713	-0.544	.002	.004	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 644 associations by consensus.

ATP6V1E2 vs THBS1_S1059 — BRCA

Explore this scatter interactively →