ATP6V1C2

Across TCGA cell cohorts, ATP6V1C2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ATP6V1C2-associated genes across cancer lineages are OR2F2 and OR13C7. Each is linked with ATP6V1C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1C2-to-partner and partner-to-ATP6V1C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2F2 grouped by ATP6V1C2-low versus ATP6V1C2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1C2→partner) and Y-score (partner→ATP6V1C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2F2 →	+0.036	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR13C7 →	+0.049	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2F2 by ATP6V1C2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →