ATP6V1B1-AS1

Across TCGA pan-cancer cohorts, ATP6V1B1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ATP6V1B1-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ATP6V1B1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP6V1B1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and ESCA show a favorable association.

KIRP, ACC, and KIRC are the cancer types where ATP6V1B1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.748	0.904	<.001	163	view →
ACC	DFS	Median	All	0.250	0.743	<.001	108	view →
KIRC	DFS	Median	All	0.536	0.697	<.001	103	view →
HNSC	DFS	Tertile	All	0.625	0.758	<.001	81	view →
UCEC	DFS	Tertile	All	0.853	0.932	<.001	50	view →
UVM	DFS	Median	II,III,IV	0.923	0.551	.002	47	view →
COAD	DFS	Tertile	All	0.702	0.810	.002	44	view →
MESO	OS	Quartile	III,IV	0.249	0.526	.004	26	view →
CESC	DFS	Quartile	All	0.735	0.863	.003	26	view →
OV	OS	Median	All	0.792	0.888	.002	24	view →
LGG	OS	Quartile	All	0.718	0.891	<.001	23	view →
READ	OS	Tertile	All	0.756	0.951	.003	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ATP6V1B1-AS1–KIRP (DFS)

Open the KIRP breakdown →