ATP6V1B1-AS1

Across TCGA pan-cancer cohorts, ATP6V1B1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ATP6V1B1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATP6V1B1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP6V1B1-AS1 is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.

HNSC, KICH, and BLCA are the cancer types where ATP6V1B1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V1B1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.185	.001	9	view →
KICH	Male	All	+0.691	<.001	8	view →
BLCA	All	III,IV	+0.142	<.001	7	view →
LUSC	All	II,III,IV	+0.471	<.001	5	view →
STAD	Male	II,III,IV	+0.152	.009	4	view →
LUAD	All	All	+0.116	.002	4	view →
BRCA	All	III,IV	−0.156	.003	2	view →
KIRC	Male	All	−0.068	.019	2	view →
READ	Female	All	−0.082	.037	1	view →
THCA	All	IV	−0.077	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ATP6V1B1-AS1–HNSC

Open the HNSC breakdown →