ATP6V1A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V1A protein abundance is significantly associated with the RNA expression of many other genes, with 11,456 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP6V1A-associated genes across cancer lineages are ATP6V1B2, FCGR1A, and FCER1G. Each is linked with ATP6V1A in more than 7 cancer types. Because this analysis shows association rather than direction, both ATP6V1A-to-partner and partner-to-ATP6V1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1A versus ATP6V1B2 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1A→partner) and Y-score (partner→ATP6V1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVATP6V1B2 →+0.640+0.239.001.00538
COADFCGR1A →+0.775+0.165.002.00236
COADFCER1G →+0.813+0.206<.001<.00136
LUADFCGR1B →+0.548+0.186<.001<.00136
COADCTSB →+0.850+0.255<.001<.00136
COADHAVCR2 →+0.830+0.247<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,456 associations by consensus.

ATP6V1A vs ATP6V1B2 — OV

Per-sample scatter of ATP6V1A vs ATP6V1B2 in OV (Pearson r = 0.34).

Explore this scatter interactively →

Exploration