ATP6V0E1P4

Across TCGA pan-cancer cohorts, ATP6V0E1P4 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ATP6V0E1P4 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher ATP6V0E1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP6V0E1P4 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

CHOL, KIRP, and BRCA are the cancer types where ATP6V0E1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	III,IV	0.031	0.505	.003	54	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	45	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
BLCA	OS	Tertile	All	0.877	0.696	.017	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
COAD	DFS	Tertile	II,III,IV	0.425	0.750	.013	27	view →
READ	DFS	Tertile	All	0.233	0.702	.006	18	view →
LGG	DFS	Tertile	All	0.691	0.839	.008	18	view →
STAD	OS	Quartile	II,III,IV	0.490	0.761	.003	6	view →
THCA	DFS	Tertile	III,IV	0.703	0.873	.028	6	view →
KIRC	OS	Quartile	II,III,IV	0.425	0.559	.028	5	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ATP6V0E1P4–CHOL (DFS)

Open the CHOL breakdown →