ATP6V0E1P4

Across TCGA pan-cancer cohorts, ATP6V0E1P4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATP6V0E1P4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ATP6V0E1P4 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP6V0E1P4 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRP, KIRC, and CHOL are the cancer types where ATP6V0E1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V0E1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.040	.021	3	view →
KIRC	All	All	+0.060	.004	2	view →
CHOL	All	All	+0.323	.032	1	view →
LUAD	All	II,III,IV	+0.064	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATP6V0E1P4–KIRP

Open the KIRP breakdown →