ATP6V0E1P3

Across TCGA pan-cancer cohorts, ATP6V0E1P3 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ATP6V0E1P3 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ATP6V0E1P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP6V0E1P3 expression acts as an unfavorable survival marker, although some lineages such as OV and READ show a favorable association.

THCA, OV, and UCS are the cancer types where ATP6V0E1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	III,IV	0.204	0.808	<.001	75	view →
OV	DFS	Median	IV	0.631	0.328	<.001	54	view →
UCS	DFS	Tertile	All	0.182	0.488	.012	36	view →
MESO	OS	Tertile	All	0.130	0.588	<.001	36	view →
PCPG	DFS	Tertile	All	0.627	0.906	<.001	36	view →
READ	OS	Tertile	All	1.000	0.582	.023	33	view →
COAD	OS	Tertile	IV	1.000	0.544	.010	24	view →
KIRP	DFS	Tertile	IV	0.036	0.458	.035	18	view →
TGCT	DFS	Tertile	All	0.954	0.615	.023	18	view →
STAD	OS	Quartile	III,IV	0.419	0.636	.024	12	view →
LIHC	DFS	Tertile	All	0.391	0.569	.032	12	view →
DLBC	DFS	Quartile	III,IV	0.070	0.833	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ATP6V0E1P3–THCA (OS)

Open the THCA breakdown →