ATP6V0E1P3

Across TCGA pan-cancer cohorts, ATP6V0E1P3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATP6V0E1P3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP6V0E1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP6V0E1P3 is over-expressed in tumor, although a few such as ESCA and LUAD show the opposite, repressed pattern.

COAD, ESCA, and PRAD are the cancer types where ATP6V0E1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V0E1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.260	.033	4	view →
ESCA	All	II,III,IV	−0.255	<.001	2	view →
PRAD	All	All	+0.071	.015	2	view →
LUAD	All	II,III,IV	−0.073	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATP6V0E1P3–COAD

Open the COAD breakdown →