ATP6V0D1

Across TCGA patient cohorts, ATP6V0D1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0D1-associated genes across cancer lineages are CD8+ naive T-cells, Macrophages, and CD4+ memory T-cells. Each is linked with ATP6V0D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP6V0D1-to-partner and partner-to-ATP6V0D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by ATP6V0D1-low versus ATP6V0D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0D1→partner) and Y-score (partner→ATP6V0D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.029	+2.354	.016	.018	3	3
COAD	Macrophages →	+0.032	+3.703	.001	.011	3	2
COAD	CD4+ memory T-cells →	+0.023	+3.543	.004	.011	3	2
COAD	MPP →	+0.024	+3.818	.012	.009	3	1
UCEC	Class-switched memory B-cells →	-0.058	-3.807	.023	<.001	3	1
UCEC	mv Endothelial cells →	-0.024	-1.989	.024	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CD8+ naive T-cells by ATP6V0D1 expression — UCEC

Explore this box plot interactively →