ATP6V0D1

Across TCGA pan-cancer cohorts, ATP6V0D1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ATP6V0D1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ATP6V0D1 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP6V0D1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, LIHC, and THCA are the cancer types where ATP6V0D1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V0D1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	−0.660	<.001	11	view →
LIHC	Female	II,III,IV	+1.085	<.001	9	view →
THCA	Male	III,IV	−0.729	<.001	9	view →
COAD	Male	All	−0.612	<.001	9	view →
KICH	All	II,III,IV	−0.590	<.001	9	view →
KIRC	Male	II,III,IV	−0.645	<.001	8	view →
HNSC	All	All	+0.320	<.001	8	view →
LUSC	Male	II,III,IV	−0.868	<.001	6	view →
CHOL	All	All	+1.193	<.001	5	view →
BRCA	All	III,IV	+0.314	.007	4	view →
READ	All	All	−0.828	.008	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ATP6V0D1–LUAD

Open the LUAD breakdown →