ATP6V0D1

Across TCGA cell cohorts, ATP6V0D1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V0D1-associated genes across cancer lineages are ADAM2, ALPI, and PRR23B. Each is linked with ATP6V0D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0D1-to-partner and partner-to-ATP6V0D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM2 grouped by ATP6V0D1-low versus ATP6V0D1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0D1→partner) and Y-score (partner→ATP6V0D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM2 →	+0.153	+5.539	<.001	.003	3	1
BLOOD_Leukemia	ALPI →	+0.006	+5.201	<.001	.006	3	1
BLOOD_Leukemia	PRR23B →	+0.006	+5.539	<.001	.003	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ADAM2 by ATP6V0D1 expression — BLOOD_Leukemia

Explore this box plot interactively →