ATP6V0B

Across TCGA patient cohorts, ATP6V0B protein abundance is significantly associated with the RNA expression of many other genes, with 7,614 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP6V0B-associated genes across cancer lineages are STIM2, SLC35D1, and NIPSNAP3B. Each is linked with ATP6V0B in more than 7 cancer types. Because this analysis shows association rather than direction, both ATP6V0B-to-partner and partner-to-ATP6V0B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V0B versus STIM2 in LSCC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0B→partner) and Y-score (partner→ATP6V0B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STIM2 →	+0.673	+0.474	<.001	<.001	3	8
LSCC	SLC35D1 →	+0.570	+0.381	<.001	<.001	3	3
LSCC	NIPSNAP3B →	-0.380	-0.286	.002	.002	3	3
OV	ARHGAP42 →	+0.904	+0.405	<.001	<.001	3	3
GBM	SLCO3A1 →	-0.938	-0.326	<.001	<.001	3	3
GBM	MTURN →	-1.164	-0.233	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,614 associations by consensus.

ATP6V0B vs STIM2 — LSCC

Explore this scatter interactively →