ATP6V0B

Across TCGA cell cohorts, ATP6V0B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,183 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V0B-associated GO terms across cancer lineages are Protein delipidation, Regulation of focal adhesion assembly, and Regulation of cell-substrate junction assembly. Each is linked with ATP6V0B in more than 9 cancer types. Because this analysis shows association rather than direction, both ATP6V0B-to-partner and partner-to-ATP6V0B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein delipidation grouped by ATP6V0B-low versus ATP6V0B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0B→partner) and Y-score (partner→ATP6V0B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein delipidation →	+0.088	+1.073	<.001	<.001	3	10
SKIN	Regulation of focal adhesion assembly →	-0.080	-0.541	<.001	.001	3	8
SKIN	Regulation of cell-substrate junction assembly →	-0.080	-0.541	<.001	.001	3	8
BLOOD_Leukemia	Negative regulation of telomere maintenance via telomere lengthening →	-0.057	-0.614	<.001	<.001	3	8
KIDNEY	Riboflavin metabolic process →	+0.183	+0.773	.005	<.001	3	8
LARGE_INTESTINE	Regulation of transforming growth factor beta3 production →	-0.112	-0.454	.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,183 associations by consensus.

Protein delipidation by ATP6V0B expression — PANCREAS

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