ATP6V0A1

Across TCGA patient cohorts, ATP6V0A1 mutation is significantly associated with the RNA expression of many other genes, with 2,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0A1-associated genes across cancer lineages are CENPM, CCDC75P1, and SNRPD1. Each is linked with ATP6V0A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP6V0A1-to-partner and partner-to-ATP6V0A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPM grouped by ATP6V0A1-low versus ATP6V0A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0A1→partner) and Y-score (partner→ATP6V0A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+0.666	+3.754	<.001	<.001	3	3
CESC	CCDC75P1 →	+0.050	+3.816	<.001	.007	3	3
UCEC	SNRPD1 →	+0.383	+2.526	.004	.001	3	3
UCEC	GLRX5 →	+0.313	+2.161	.006	.002	3	3
UCEC	RN7SKP256 →	+0.147	+2.095	<.001	.007	3	3
SKCM	KTN1-AS1 →	+0.517	+2.706	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,834 associations by consensus.

CENPM by ATP6V0A1 expression — UCEC

Explore this box plot interactively →