ATP6V0A1

Across TCGA cell cohorts, ATP6V0A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,135 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V0A1-associated GO terms across cancer lineages are Endosomal lumen acidification, Vacuolar acidification, and Synaptic vesicle lumen acidification. Each is linked with ATP6V0A1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATP6V0A1-to-partner and partner-to-ATP6V0A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal lumen acidification grouped by ATP6V0A1-low versus ATP6V0A1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0A1→partner) and Y-score (partner→ATP6V0A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosomal lumen acidification →	+0.173	+1.226	<.001	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	Vacuolar acidification →	+0.098	+1.140	<.001	<.001	3	15
BLOOD_Myeloma	Synaptic vesicle lumen acidification →	+0.175	+0.743	<.001	.008	3	14
BLOOD_Lymphoma	Cytosolic transport →	+0.064	+1.810	<.001	<.001	3	13
STOMACH	Regulation of TORC1 signaling →	+0.096	+1.207	<.001	.001	3	12
LUNG_SCLC	Establishment of vesicle localization →	+0.068	+0.886	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,135 associations by consensus.

Endosomal lumen acidification by ATP6V0A1 expression — STOMACH

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