ATP5POP1

Across TCGA pan-cancer cohorts, ATP5POP1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated ATP5POP1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ATP5POP1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP5POP1 expression acts as an unfavorable survival marker, although some lineages such as THCA and LUAD show a favorable association.

THCA, LUAD, and CHOL are the cancer types where ATP5POP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.942	0.780	<.001	43	view →
LUAD	DFS	Tertile	II,III,IV	0.424	0.205	.017	32	view →
CHOL	OS	Tertile	II,III,IV	0.080	0.740	.026	27	view →
READ	DFS	Tertile	III,IV	0.612	0.267	.010	26	view →
OV	OS	Quartile	II,III,IV	0.793	0.887	.005	20	view →
KIRP	OS	Median	All	0.916	0.590	.004	14	view →
KIRC	DFS	Median	II,III,IV	0.856	0.758	.023	12	view →
MESO	OS	Tertile	IV	0.155	0.624	.004	12	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
BLCA	DFS	Tertile	III,IV	0.542	0.317	.034	6	view →
ACC	OS	Tertile	IV	1.000	0.360	.049	6	view →
ESCA	OS	Tertile	IV	0.713	0.264	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

ATP5POP1–THCA (DFS)

Open the THCA breakdown →