Q-omics provides the consensus-scored ATP5POP1 profile across patient tissues and cancer cell-line models. ATP5POP1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, ATP5POP1 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, ATP5POP1 RNA expression shows 5,262 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight THCA, COAD, and STAD as cancer lineages where ATP5POP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ATP5POP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ATP5POP1 survival associations across molecular data types. ATP5POP1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ATP5POP1 RNA expression–survival associations across cancer types. High ATP5POP1 expression shows unfavorable associations in CHOL and OV, but favorable associations in THCA, LUAD, READ and KIRP. The THCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for ATP5POP1 RNA expression.
This table summarizes ATP5POP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for ATP5POP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ATP5POP1 shows lower tumor expression in PAAD, COAD, READ and THCA and higher tumor expression in COAD and BRCA. The COAD box plot shows higher ATP5POP1 RNA expression in tumor versus normal tissue (log2 FC = +0.143, t-test p = .024).
This table shows molecular features associated with ATP5POP1 in patient tissues and cancer cell lines. In patient samples, ATP5POP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
