ATP5PO

Across TCGA patient cohorts, ATP5PO protein abundance is significantly associated with the RNA expression of many other genes, with 8,603 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP5PO-associated genes across cancer lineages are CKMT1A, ALOX5AP, and HERC5. Each is linked with ATP5PO in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP5PO-to-partner and partner-to-ATP5PO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5PO versus CKMT1A in PDAC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PO→partner) and Y-score (partner→ATP5PO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CKMT1A →	+0.807	+0.293	<.001	.002	3	4
BRCA	ALOX5AP →	-0.645	-0.268	<.001	<.001	3	4
LSCC	HERC5 →	-0.903	-0.221	<.001	<.001	3	4
LUAD	DCBLD1 →	-0.766	-0.327	<.001	<.001	3	4
COAD	SPARC →	-1.083	-0.211	<.001	.003	3	4
COAD	TREM1 →	-0.940	-0.174	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,603 associations by consensus.

ATP5PO vs CKMT1A — PDAC

Explore this scatter interactively →