ATP5PO

Across TCGA cell cohorts, ATP5PO RNA expression is significantly associated with the go_rna of many other GO terms, with 3,384 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATP5PO-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial translational elongation, and Regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with ATP5PO in more than 12 cancer types. Because this analysis shows association rather than direction, both ATP5PO-to-partner and partner-to-ATP5PO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by ATP5PO-low versus ATP5PO-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PO→partner) and Y-score (partner→ATP5PO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial translation →	+0.134	+0.686	<.001	<.001	3	13
BONE	Mitochondrial translational elongation →	+0.124	+0.589	<.001	<.001	3	12
BONE	Regulation of tumor necrosis factor-mediated signaling pathway →	-0.085	-0.789	<.001	<.001	3	11
PANCREAS	Quinone biosynthetic process →	+0.092	+0.544	.001	.003	2	12
OESOPHAGUS	Cerebral cortex radial glia-guided migration →	-0.149	-0.881	.002	.005	3	11
OESOPHAGUS	Telencephalon glial cell migration →	-0.149	-0.881	.002	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,384 associations by consensus.

Mitochondrial translation by ATP5PO expression — BONE

Explore this box plot interactively →