ATP5PF

Across TCGA patient cohorts, ATP5PF mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5PF-associated genes across cancer lineages are IGLVIV-53, OR5AR1, and ELOCP14. Each is linked with ATP5PF in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5PF-to-partner and partner-to-ATP5PF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGLVIV-53 grouped by ATP5PF-low versus ATP5PF-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PF→partner) and Y-score (partner→ATP5PF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	IGLVIV-53 →	+0.094	+7.816	<.001	.008	3	1
SKCM	OR5AR1 →	+0.334	+7.816	<.001	.008	3	1
SKCM	ELOCP14 →	+0.104	+7.816	<.001	.008	3	1
UCEC	SNRPGP17 →	+0.357	+3.200	.005	.005	3	1
UCEC	HNRNPCL3 →	+0.049	+3.608	.006	.002	3	1
UCEC	SEPTIN14 →	+0.571	+3.598	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

IGLVIV-53 by ATP5PF expression — SKCM

Explore this box plot interactively →