ATP5PD

Across TCGA patient cohorts, ATP5PD protein abundance is significantly associated with the RNA expression of many other genes, with 11,371 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP5PD-associated genes across cancer lineages are PDLIM7, COL15A1, and SFRP4. Each is linked with ATP5PD in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP5PD-to-partner and partner-to-ATP5PD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5PD versus PDLIM7 in LSCC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PD→partner) and Y-score (partner→ATP5PD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDLIM7 →	-0.914	-0.370	<.001	<.001	3	7
LSCC	COL15A1 →	-1.387	-0.308	<.001	<.001	3	7
COAD	SFRP4 →	-2.059	-0.297	<.001	<.001	3	6
OV	LAMA4 →	-1.068	-0.485	.001	<.001	3	6
OV	FN1 →	-1.696	-0.339	<.001	<.001	3	6
CCRCC	PTGIS →	-1.503	-0.255	.001	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,371 associations by consensus.

ATP5PD vs PDLIM7 — LSCC

Explore this scatter interactively →