ATP5PD

Across TCGA patient cohorts, ATP5PD mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5PD-associated genes across cancer lineages are RNU6-222P, PANDAR, and MIR4804. Each is linked with ATP5PD in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5PD-to-partner and partner-to-ATP5PD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-222P grouped by ATP5PD-low versus ATP5PD-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PD→partner) and Y-score (partner→ATP5PD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-222P →	+0.629	+3.809	.001	.007	3	2
UCEC	PANDAR →	+0.047	+3.840	.006	.007	3	1
UCEC	MIR4804 →	+0.749	+4.718	<.001	.001	3	1
UCEC	RN7SL178P →	+0.233	+5.356	<.001	<.001	3	1
LUSC	RNU6-266P →	+0.438	+7.924	<.001	.008	3	1
UCEC	IL21 →	+0.209	+4.026	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

RNU6-222P by ATP5PD expression — UCEC

Explore this box plot interactively →