ATP5PD

Across TCGA cell cohorts, ATP5PD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,521 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP5PD-associated GO terms across cancer lineages are Response to forskolin, Epigenetic programing of male pronucleus, and RNA destabilization. Each is linked with ATP5PD in more than 10 cancer types. Because this analysis shows association rather than direction, both ATP5PD-to-partner and partner-to-ATP5PD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to forskolin grouped by ATP5PD-low versus ATP5PD-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PD→partner) and Y-score (partner→ATP5PD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Response to forskolin →	-0.145	-0.527	<.001	<.001	3	11
SKIN	Epigenetic programing of male pronucleus →	+0.122	+0.529	<.001	<.001	3	10
BLOOD_Leukemia	RNA destabilization →	-0.044	-0.458	<.001	.002	3	10
BONE	Positive regulation of RNA polymerase II transcription preinitiation complex assembly →	-0.172	-0.750	<.001	<.001	3	9
SOFT_TISSUE	Pyruvate import into mitochondria →	+0.158	+0.637	<.001	<.001	3	9
BONE	Viral translational termination-reinitiation →	-0.089	-0.762	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,521 associations by consensus.

Response to forskolin by ATP5PD expression — LARGE_INTESTINE

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