ATP5PBP5

Across TCGA patient cohorts, ATP5PBP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ATP5PBP5-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Regulation of macroautophagy, and Hippo signaling. Each is linked with ATP5PBP5 in more than 31 cancer types. Because this analysis shows association rather than direction, both ATP5PBP5-to-partner and partner-to-ATP5PBP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical NF-kappaB signal transduction grouped by ATP5PBP5-low versus ATP5PBP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PBP5→partner) and Y-score (partner→ATP5PBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.057	+0.418	<.001	<.001	3	32
STAD	Regulation of macroautophagy →	+0.062	+0.452	<.001	<.001	3	31
THYM	Hippo signaling →	+0.068	+1.148	<.001	<.001	3	31
THYM	Golgi vesicle transport →	+0.057	+1.183	<.001	<.001	3	31
THYM	Positive regulation of autophagosome assembly →	+0.087	+1.198	<.001	<.001	3	31
STAD	Lamellipodium organization →	+0.058	+0.524	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Positive regulation of canonical NF-kappaB signal transduction by ATP5PBP5 expression — STAD

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