ATP5MGP6

Across TCGA pan-cancer cohorts, ATP5MGP6 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated ATP5MGP6 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ATP5MGP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5MGP6 expression acts as an unfavorable survival marker, although some lineages such as GBM and STAD show a favorable association.

UVM, DLBC, and HNSC are the cancer types where ATP5MGP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.265	0.699	.003	54	view →
DLBC	DFS	Tertile	All	0.104	0.912	<.001	45	view →
HNSC	OS	Tertile	II,III,IV	0.458	0.656	.020	30	view →
GBM	OS	Tertile	All	0.575	0.338	.015	19	view →
KIRP	OS	Tertile	II,III,IV	0.141	0.673	.017	18	view →
STAD	DFS	Quartile	IV	0.831	0.192	.016	17	view →
LAML	DFS	Tertile	All	0.406	0.656	.018	12	view →
THCA	OS	Tertile	III,IV	0.240	0.794	.045	9	view →
SARC	DFS	Tertile	All	0.222	0.611	<.001	9	view →
MESO	OS	Tertile	All	0.875	0.524	.042	6	view →
UCS	OS	Tertile	III,IV	0.899	0.505	.039	6	view →
LIHC	DFS	Tertile	All	0.424	0.570	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

ATP5MGP6–UVM (OS)

Open the UVM breakdown →