Across TCGA pan-cancer cohorts, ATP5MGP6 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ATP5MGP6’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where ATP5MGP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5MGP6 is over-expressed in tumor.
ESCA and PRAD are the cancer types where ATP5MGP6 tumor–normal differential expression is most reproducible.