ATP5MGL

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP5MGL mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5MGL-associated genes across cancer lineages are LINC01338, SEPTIN14P19, and HERC2P7. Each is linked with ATP5MGL in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MGL-to-partner and partner-to-ATP5MGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01338 grouped by ATP5MGL-low versus ATP5MGL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MGL→partner) and Y-score (partner→ATP5MGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01338 →+0.466+3.730<.001.00631
UCECSEPTIN14P19 →+0.044+4.923<.001.00231
UCECHERC2P7 →+0.093+3.329<.001.00431
UCECRNU6-618P →+0.412+3.800.003.00131
UCECRNA5SP28 →+1.203+3.109<.001.00731
UCECSNORD82 →+0.773+3.776.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

LINC01338 by ATP5MGL expression — UCEC

Box plot of LINC01338 in ATP5MGL-low vs ATP5MGL-high samples in UCEC.

Explore this box plot interactively →

Exploration