ATP5MFP3

Across TCGA pan-cancer cohorts, ATP5MFP3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated ATP5MFP3 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ATP5MFP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5MFP3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUSC show a favorable association.

SKCM, KIRP, and READ are the cancer types where ATP5MFP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.629	0.882	<.001	81	view →
KIRP	DFS	Tertile	All	0.720	0.892	<.001	71	view →
READ	OS	Tertile	III,IV	0.289	0.932	<.001	45	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
PAAD	DFS	Tertile	All	0.060	0.468	<.001	18	view →
ESCA	OS	Quartile	III,IV	0.682	0.414	.047	18	view →
LIHC	OS	Tertile	III,IV	0.059	0.738	<.001	18	view →
ACC	DFS	Tertile	III,IV	0.048	0.457	.015	18	view →
LUSC	DFS	Tertile	All	0.696	0.379	.019	12	view →
THCA	DFS	Tertile	IV	0.514	0.937	<.001	12	view →
COAD	OS	Tertile	IV	0.243	0.654	.048	9	view →
KIRC	DFS	Tertile	All	0.864	0.776	.028	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

ATP5MFP3–SKCM (OS)

Open the SKCM breakdown →