ATP5ME

Across TCGA patient cohorts, ATP5ME RNA expression is significantly associated with the go_rna of many other GO terms, with 7,166 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible ATP5ME-associated GO terms across cancer lineages are Ribosome-associated ubiquitin-dependent protein catabolic process, Lysosomal transport, and Insulin receptor signaling pathway. Each is linked with ATP5ME in more than 27 cancer types. Because this analysis shows association rather than direction, both ATP5ME-to-partner and partner-to-ATP5ME results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome-associated ubiquitin-dependent protein catabolic process grouped by ATP5ME-low versus ATP5ME-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5ME→partner) and Y-score (partner→ATP5ME) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Ribosome-associated ubiquitin-dependent protein catabolic process →	-0.099	-1.011	<.001	<.001	3	28
THYM	Lysosomal transport →	-0.058	-1.067	<.001	<.001	3	28
THYM	Insulin receptor signaling pathway →	-0.072	-1.057	<.001	<.001	3	28
UCS	Vesicle cargo loading →	-0.091	-1.077	<.001	<.001	3	28
THYM	Regulation of ERBB signaling pathway →	-0.052	-0.941	<.001	<.001	3	27
THYM	Regulation of lamellipodium organization →	-0.069	-0.968	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,166 associations by consensus.

Ribosome-associated ubiquitin-dependent protein catabolic process by ATP5ME expression — THYM

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