ATP5ME

Across TCGA patient cohorts, ATP5ME protein abundance is significantly associated with the RNA expression of many other genes, with 8,864 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP5ME-associated genes across cancer lineages are CTHRC1, CAVIN1, and MRC2. Each is linked with ATP5ME in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP5ME-to-partner and partner-to-ATP5ME results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5ME versus CTHRC1 in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5ME→partner) and Y-score (partner→ATP5ME) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTHRC1 →	-1.154	-0.305	<.001	<.001	3	5
UCEC	CAVIN1 →	-1.006	-0.336	<.001	.001	3	5
UCEC	MRC2 →	-0.940	-0.320	<.001	<.001	3	4
OV	MFAP2 →	-1.695	-0.279	<.001	.006	3	4
OV	P3H1 →	-0.912	-0.358	<.001	<.001	3	4
GBM	CALU →	-0.625	-0.283	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,864 associations by consensus.

ATP5ME vs CTHRC1 — GBM

Explore this scatter interactively →