ATP5ME

Across TCGA patient cohorts, ATP5ME mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5ME-associated genes across cancer lineages are RNA5SP414, SNX3P1Y, and MIR6854. Each is linked with ATP5ME in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5ME-to-partner and partner-to-ATP5ME results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by ATP5ME-low versus ATP5ME-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5ME→partner) and Y-score (partner→ATP5ME) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+1.174	+3.840	<.001	.007	3	1
BLCA	SNX3P1Y →	+0.249	+7.640	<.001	.009	3	1
UCEC	MIR6854 →	+0.453	+4.997	<.001	.003	3	1
UCEC	RN7SL134P →	+0.304	+4.184	<.001	.003	3	1
UCEC	MIA-RAB4B →	+0.133	+3.863	<.001	.008	3	1
UCEC	RNA5SP319 →	+0.676	+4.061	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RNA5SP414 by ATP5ME expression — UCEC

Explore this box plot interactively →