ATP5MD

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ATP5MD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,058 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP5MD-associated GO terms across cancer lineages are Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration, Negative regulation of DNA-templated transcription initiation, and Negative regulation of cytoplasmic pattern recognition receptor signaling pathway. Each is linked with ATP5MD in more than 14 cancer types. Because this analysis shows association rather than direction, both ATP5MD-to-partner and partner-to-ATP5MD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration grouped by ATP5MD-low versus ATP5MD-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MD→partner) and Y-score (partner→ATP5MD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSModulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →-0.141-0.814.002.003315
OESOPHAGUSNegative regulation of DNA-templated transcription initiation →-0.162-1.227<.001.001315
OESOPHAGUSNegative regulation of cytoplasmic pattern recognition receptor signaling pathway →-0.152-1.301<.001<.001315
OESOPHAGUSNegative regulation of transcription initiation by RNA polymerase II →-0.162-1.227<.001.001315
UPPER_AERODIGESTIVE_TRACTNegative regulation of autophagy →-0.068-0.985<.001<.001315
BONENegative regulation of protein-containing complex assembly →-0.090-0.830<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,058 associations by consensus.

Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration by ATP5MD expression — OESOPHAGUS

Box plot of Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration in ATP5MD-low vs ATP5MD-high samples in OESOPHAGUS.

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Exploration