ATP5MC3

Across TCGA patient cohorts, ATP5MC3 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5MC3-associated genes across cancer lineages are MIR3193, MIA-RAB4B, and IGHV3OR16-6. Each is linked with ATP5MC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MC3-to-partner and partner-to-ATP5MC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3193 grouped by ATP5MC3-low versus ATP5MC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MC3→partner) and Y-score (partner→ATP5MC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3193 →	+1.118	+3.160	<.001	.002	3	1
UCEC	MIA-RAB4B →	+0.125	+3.670	<.001	<.001	3	1
UCEC	IGHV3OR16-6 →	+0.557	+3.204	.008	.002	3	1
UCEC	IGKV1OR2-118 →	+0.249	+2.818	.007	.005	3	1
UCEC	MIR8082 →	+0.499	+3.239	<.001	.003	3	1
UCEC	SPZ1 →	+0.225	+3.314	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

MIR3193 by ATP5MC3 expression — UCEC

Explore this box plot interactively →