ATP5MC3

Across TCGA cell cohorts, ATP5MC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,641 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP5MC3-associated GO terms across cancer lineages are 'de novo' UMP biosynthetic process, Quinone metabolic process, and Ubiquinone metabolic process. Each is linked with ATP5MC3 in more than 14 cancer types. Because this analysis shows association rather than direction, both ATP5MC3-to-partner and partner-to-ATP5MC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' UMP biosynthetic process grouped by ATP5MC3-low versus ATP5MC3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MC3→partner) and Y-score (partner→ATP5MC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	'de novo' UMP biosynthetic process →	+0.138	+0.560	<.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	Quinone metabolic process →	+0.100	+1.349	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Ubiquinone metabolic process →	+0.097	+1.329	<.001	<.001	3	13
URINARY_TRACT	Nucleotide biosynthetic process →	+0.077	+0.868	.005	.004	3	13
LUNG_NSCLC_LUAD	Ketone metabolic process →	+0.120	+0.891	<.001	<.001	3	13
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.084	+0.830	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,641 associations by consensus.

'de novo' UMP biosynthetic process by ATP5MC3 expression — PANCREAS

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