ATP5MC1

Across TCGA cell cohorts, ATP5MC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,882 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ATP5MC1-associated GO terms across cancer lineages are Protein stabilization, [2Fe-2S] cluster assembly, and Aromatic amino acid metabolic process. Each is linked with ATP5MC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ATP5MC1-to-partner and partner-to-ATP5MC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by ATP5MC1-low versus ATP5MC1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MC1→partner) and Y-score (partner→ATP5MC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein stabilization →	-0.067	-1.031	<.001	<.001	3	14
BLOOD_Leukemia	[2Fe-2S] cluster assembly →	+0.105	+0.618	<.001	.002	3	14
LARGE_INTESTINE	Aromatic amino acid metabolic process →	+0.194	+1.097	<.001	<.001	3	13
URINARY_TRACT	Ketone metabolic process →	+0.112	+0.931	.001	.005	3	13
PANCREAS	Ketone biosynthetic process →	+0.108	+0.917	.001	<.001	3	13
BONE	Small GTPase-mediated signal transduction →	-0.054	-1.002	.003	.005	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,882 associations by consensus.

Protein stabilization by ATP5MC1 expression — LARGE_INTESTINE

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